Cell-cycle-phase progression analysis identifies unique phenotypes of major prognostic and predictive significance in breast cancer

Multiparameter analysis of core regulatory proteins involved in G1–S and G2–M cell-cycle transitions provides a powerful biomarker readout for assessment of the cell-cycle state. We have applied this algorithm to breast cancer to investigate how the cell cycle impacts on disease progression. Protein...

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Detalhes bibliográficos
Main Authors: Loddo, M, Kingsbury, S R, Rashid, M, Proctor, I, Holt, C, Young, J, El-Sheikh, S, Falzon, M, Eward, K L, Prevost, T, Sainsbury, R, Stoeber, K, Williams, G H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661794/
https://ncbi.nlm.nih.gov/pubmed/19240714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604924
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