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Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

Neuritic retraction represents a prominent feature of the degenerative phenotype associated with mutations in leucine rich repeat kinase 2 (LRRK2) that are implicated in autosomal dominant and some cases of sporadic Parkinson's disease. Alterations in macroautophagy, the vacuolar catabolism of...

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Hlavní autoři: Plowey, Edward D., Cherra, Salvatore J., Liu, Yong-Jian, Chu, Charleen T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361385/
https://ncbi.nlm.nih.gov/pubmed/18182054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05217.x
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