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Mutations of the transcription factor PU.1 are not associated with acute lymphoblastic leukaemia
The transcription factor PU.1 plays a crucial role during normal haematopoiesis in both myeloid cells and B-lymphocytes. Mice with a disruption in both alleles of the PU.1 locus were found to lack macrophages and B cells and had delayed appearance of neutrophils. In addition, critical decrease of PU...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group
2006
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361337/ https://ncbi.nlm.nih.gov/pubmed/16735999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603198 |
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