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Mutation of the PIK3CA oncogene in human cancers

It is now well established that cancer is a genetic disease and that somatic mutations of oncogenes and tumour suppressor genes are the initiators of the carcinogenic process. The phosphatidylinositol 3-kinase signalling pathway has previously been implicated in tumorigenesis, and evidence over the...

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Библиографические подробности
Главные авторы: Karakas, B, Bachman, K E, Park, B H
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361173/
https://ncbi.nlm.nih.gov/pubmed/16449998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602970
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