The status of CDKN2A alpha (p16(INK4A)) and beta (p14(ARF)) transcripts in thyroid tumour progression

CDKN2A locus on chromosome 9p21 encodes two tumour suppressor proteins pl6(INK4A), which is a regulator of the retinoblastoma (RB) protein, and p14(ARF), which is involved in the ARF–Mdm2–p53 pathway. The aim of this study was to determine if CDKN2A gene products are implicated in differentiated thy...

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Hlavní autoři: Ferru, A, Fromont, G, Gibelin, H, Guilhot, J, Savagner, F, Tourani, J M, Kraimps, J L, Larsen, C J, Karayan-Tapon, L
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2006
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360765/
https://ncbi.nlm.nih.gov/pubmed/17117177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603479
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