Survey of familial glioma and role of germline p16(INK4A)/p14(ARF) and p53 mutation

There is increasing recognition of familial propensity to glioma as a distinct clinical entity beyond a few rare syndromes; however its genetic basis is poorly understood. The role of p16(INK4A)/p14(ARF) and p53 mutations in sporadic glioma provides a strong rationale for investigating germline muta...

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Autors principals: Robertson, Lindsay B, Armstrong, Georgina N, Olver, Bianca D, Lloyd, Amy L, Shete, Sanjay, Lau, Ching, Claus, Elizabeth B, Barnholtz-Sloan, Jill, Lai, Rose, Il’yasova, Dora, Schildkraut, Joellen, Bernstein, Jonine L, Olson, Sara H, Jenkins, Robert B, Yang, Ping, Rynerason, Amanda L, Wrensch, Margaret, McCoy, Lucie, Wienkce, John K, McCarthy, Bridget, Davis, Faith, Vick, Nicholas A., Johansen, Christoffer, Bødtcher, Hanne, Sadetzki, Siegal, Bruchim, Revital Bar-Sade, Yechezkel, Galit Hirsh, Andersson, Ulrika, Melin, Beatrice S, Bondy, Melissa L, Houlston, Richard S
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922430/
https://ncbi.nlm.nih.gov/pubmed/20455025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-010-9346-5
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