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Comprehensive analysis of CDKN2A (p16(INK4A)/p14(ARF)) and CDKN2B genes in 53 melanoma index cases considered to be at heightened risk of melanoma

OBJECTIVE: Comprehensive analysis of the 9p21 locus including the CDKN2A, ARF, and CDKN2B genes in 53 individuals from melanoma index cases considered to be at heightened risk of melanoma. METHODS AND RESULTS: Using a combination of DNA sequencing, gene copy number by real time quantitative PCR, lin...

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Detalhes bibliográficos
Main Authors: Laud, K, Marian, C, Avril, M F, Barrois, M, Chompret, A, Goldstein, A M, Tucker, M A, Clark, P A, Peters, G, Chaudru, V, Demenais, F, Spatz, A, Smith, M W, Lenoir, G M, Paillerets, B Bressac‐de
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564502/
https://ncbi.nlm.nih.gov/pubmed/15937071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.033498
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