Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines

Cell lines are important models for drug resistance in acute lymphoblastic leukaemia (ALL), but are often criticised as being unrepresentative of primary disease. There are also doubts regarding the authenticity of many lines. We have characterised a panel of ALL cell lines for growth and drug resis...

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Main Authors: Beesley, A H, Palmer, M-L, Ford, J, Weller, R E, Cummings, A J, Freitas, J R, Firth, M J, Perera, K U, de Klerk, N H, Kees, U R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2006
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360743/
https://ncbi.nlm.nih.gov/pubmed/17117183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603447
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