Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolism

Glucocorticoids (GCs) are among the most important drugs for acute lymphoblastic leukaemia (ALL), yet despite their clinical importance, the exact mechanisms involved in GC cytotoxicity and the development of resistance remain uncertain. We examined the baseline profile of a panel of T-ALL cell line...

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Bibliographic Details
Main Authors: Beesley, A H, Firth, M J, Ford, J, Weller, R E, Freitas, J R, Perera, K U, Kees, U R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
Subjects:
Molecular Diagnostics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714233/
https://ncbi.nlm.nih.gov/pubmed/19436302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605072
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