Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia

BACKGROUND: Pre-clinical models that effectively recapitulate human disease are critical for expanding our knowledge of cancer biology and drug resistance mechanisms. For haematological malignancies, the non-obese diabetic/severe combined immunodeficient (NOD/SCID) mouse is one of the most successfu...

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Detalhes bibliográficos
Main Authors: Samuels, Amy L, Peeva, Violet K, Papa, Rachael A, Firth, Marin J, Francis, Richard W, Beesley, Alex H, Lock, Richard B, Kees, Ursula R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876122/
https://ncbi.nlm.nih.gov/pubmed/20406497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-256
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