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Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer
Colorectal cancer (CRC) develops as multistep process, which involves genetic and epigenetic alterations. K-Ras, p53 and B-Raf mutations and RASSF1A, E-Cadherin and p16INK4A promoter methylation were investigated in 202 CRCs with and without lymph node and/or liver metastasis, to assess whether gene...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2360724/ https://ncbi.nlm.nih.gov/pubmed/16969349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603337 |
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