Molecular heterogeneity and prognostic implications of synchronous advanced colorectal neoplasia

BACKGROUND: It is uncertain whether synchronous colorectal cancers (S-CRCs) preferentially develop through widespread DNA methylation and whether they have a prognosis worse than solitary CRC. As tumours with microsatellite instability (MSI) may confound the effect of S-CRC methylation on outcome, w...

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Detalhes bibliográficos
Main Authors: Malesci, A, Basso, G, Bianchi, P, Fini, L, Grizzi, F, Celesti, G, Di Caro, G, Delconte, G, Dattola, F, Repici, A, Roncalli, M, Montorsi, M, Laghi, L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950856/
https://ncbi.nlm.nih.gov/pubmed/24434431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.827
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