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TIMP-1 gene deficiency increases tumour cell sensitivity to chemotherapy-induced apoptosis
Tissue inhibitor of metalloproteinases-1 (TIMP-1) is one of four inhibitors of the matrix metalloproteinases, which are capable of degrading most components of the extracellular matrix. However, in recent years, TIMP-1 has been recognised as a multifunctional protein, playing a complex role in cance...
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Autori principali: | , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Nature Publishing Group
2006
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2360707/ https://ncbi.nlm.nih.gov/pubmed/17047657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603378 |
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