Identification of alternatively spliced TIMP‐1 mRNA in cancer cell lines and colon cancer tissue

TIMP‐1 is a promising new candidate as a prognostic marker in colorectal and breast cancer. We now describe the discovery of two alternatively spliced variants of TIMP‐1 mRNA. The two variants lacking exon 2 (del‐2) and 5 (del‐5), respectively, were identified in human cancer cell lines by RT‐PCR. T...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Usher, P.A., Sieuwerts, A.M., Bartels, A., Lademann, U., Nielsen, H.J., Holten-Andersen, L., Foekens, J.A., Brünner, N., Offenberg, H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2007
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543896/
https://ncbi.nlm.nih.gov/pubmed/19383295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2007.05.002
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