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The impact of FDA and EMEA guidelines on drug development in relation to Phase 0 trials

An increase in the number of identified therapeutic cancer targets achieved through recent biomedical research has resulted in the generation of a large number of molecules that need to be tested further. Current development of (anticancer) drugs is a rather inefficient process that for an average n...

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Detalhes bibliográficos
Main Authors: Marchetti, S, Schellens, J H M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360360/
https://ncbi.nlm.nih.gov/pubmed/17726450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603925
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