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Immunotherapy for neuroblastoma using syngeneic fibroblasts transfected with IL-2 and IL-12
Cytokine-modified tumour cells have been used in clinical trials for immunotherapy of neuroblastoma, but primary tumour cells from surgical biopsies are difficult to culture. Autologous fibroblasts, however, are straightforward to manipulate in culture and easy to transfect using nonviral or viral v...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2360308/ https://ncbi.nlm.nih.gov/pubmed/17595664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603857 |
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