Immunotherapy for neuroblastoma using syngeneic fibroblasts transfected with IL-2 and IL-12

Cytokine-modified tumour cells have been used in clinical trials for immunotherapy of neuroblastoma, but primary tumour cells from surgical biopsies are difficult to culture. Autologous fibroblasts, however, are straightforward to manipulate in culture and easy to transfect using nonviral or viral v...

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Main Authors: Barker, S E, Grosse, S M, Siapati, E K, Kritz, A, Kinnon, C, Thrasher, A J, Hart, S L
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Translational Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360308/
https://ncbi.nlm.nih.gov/pubmed/17595664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603857
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