Combined innate and adaptive immunotherapy overcomes resistance of immunologically cold syngeneic murine neuroblastoma to checkpoint inhibition

BACKGROUND: Unlike some adult cancers, most pediatric cancers are considered immunologically cold and generally less responsive to immunotherapy. While immunotherapy has already been incorporated into standard of care treatment for pediatric patients with high-risk neuroblastoma, overall survival re...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Voeller, Julie, Erbe, Amy K., Slowinski, Jacob, Rasmussen, Kayla, Carlson, Peter M., Hoefges, Anna, VandenHeuvel, Sabrina, Stuckwisch, Ashley, Wang, Xing, Gillies, Stephen D., Patel, Ravi B., Farrel, Alvin, Rokita, Jo Lynne, Maris, John, Hank, Jacquelyn A., Morris, Zachary S., Rakhmilevich, Alexander L., Sondel, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898936/
https://ncbi.nlm.nih.gov/pubmed/31810498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0823-6
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