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Transfection of IL-2 and/or IL-12 genes into spleen in treatment of rat liver cancer

AIM: To test the efficacy of gene therapy in rat liver tumor. METHODS: A retroviral vector GCIL12EIL2PN encoding human IL-2 (hIL-2) and mouse IL-12 (mIL-12) fused gene and its packaging cell were constructed. The packaging cell lines contained of IL-2 and/or IL-12 genes were injected intrasplenicall...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: You, Tian-Geng, Wang, Hong-Shun, Yang, Jia-He, Qian, Qi-Jun, Fan, Rui-Fang, Wu, Meng-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724966/
https://ncbi.nlm.nih.gov/pubmed/15259063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i15.2190
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