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Attenuation of muscle atrophy in a murine model of cachexia by inhibition of the dsRNA-dependent protein kinase

Atrophy of skeletal muscle is due to a depression in protein synthesis and an increase in degradation. Studies in vitro have suggested that activation of the dsRNA-dependent protein kinase (PKR) may be responsible for these changes in protein synthesis and degradation. In order to evaluate whether t...

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Detalhes bibliográficos
Main Authors: Eley, H L, Russell, S T, Tisdale, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360141/
https://ncbi.nlm.nih.gov/pubmed/17387345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603704
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