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High-level amplification at 17q23 leads to coordinated overexpression of multiple adjacent genes in breast cancer

Increased copy numbers of 17q23 chromosomal region have been shown to occur in different tumour types and to be associated with tumour progression and with poor prognosis. Several genes have earlier been proposed as potential oncogenes at this region largely on the grounds of cell lines studies. In...

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Detalhes bibliográficos
Main Authors: Pärssinen, J, Kuukasjärvi, T, Karhu, R, Kallioniemi, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360139/
https://ncbi.nlm.nih.gov/pubmed/17353917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603692
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