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Amplification of a 280-Kilobase Core Region at the ERBB2 Locus Leads to Activation of Two Hypothetical Proteins in Breast Cancer

Amplification of the ERBB2 oncogene at 17q12 is clinically the most relevant genetic aberration in breast cancer and several studies have linked ERBB2 activation to poor clinical outcome. The development of targeted antibody-based therapy for ERBB2-overexpressing tumors and the possible role of ERBB...

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מידע ביבליוגרפי
Main Authors: Kauraniemi, Päivikki, Kuukasjärvi, Tuula, Sauter, Guido, Kallioniemi, Anne
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Investigative Pathology 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892409/
https://ncbi.nlm.nih.gov/pubmed/14578197
תגים: הוספת תג
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