Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer

The biological significance of DNA amplification in cancer is thought to be due to the selection of increased expression of a single or few important genes. However, systematic surveys of the copy number and expression of all genes within an amplified region of the genome have not been performed. He...

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Detalhes bibliográficos
Main Authors: Monni, Outi, Bärlund, Maarit, Mousses, Spyro, Kononen, Juha, Sauter, Guido, Heiskanen, Mervi, Paavola, Paulina, Avela, Kristiina, Chen, Yidong, Bittner, Michael L., Kallioniemi, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC33278/
https://ncbi.nlm.nih.gov/pubmed/11331760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091582298
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