The novel microtubule-interfering agent TZT-1027 enhances the anticancer effect of radiation in vitro and in vivo

TZT-1027 is a novel anticancer agent that inhibits microtubule polymerisation and manifests potent antitumour activity in preclinical models. We have examined the effect of TZT-1027 on cell cycle progression as well as the anticancer activity of this drug both in vitro and in vivo. With the use of t...

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Dettagli Bibliografici
Autori principali: Akashi, Y, Okamoto, I, Suzuki, M, Tamura, K, Iwasa, T, Hisada, S, Satoh, T, Nakagawa, K, Ono, K, Fukuoka, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
Soggetti:
Translational Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359952/
https://ncbi.nlm.nih.gov/pubmed/17473826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603769
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