Enhancement of the antitumor activity of ionising radiation by nimotuzumab, a humanised monoclonal antibody to the epidermal growth factor receptor, in non-small cell lung cancer cell lines of differing epidermal growth factor receptor status

The expression and activity of the epidermal growth factor receptor (EGFR) are determinants of radiosensitivity in several tumour types, including non-small cell lung cancer (NSCLC). However, little is known of whether genetic alterations of EGFR in NSCLC cells affect the therapeutic response to mon...

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Detalhes bibliográficos
Main Authors: Akashi, Y, Okamoto, I, Iwasa, T, Yoshida, T, Suzuki, M, Hatashita, E, Yamada, Y, Satoh, T, Fukuoka, M, Ono, K, Nakagawa, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259177/
https://ncbi.nlm.nih.gov/pubmed/18253126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604222
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