(89)Zr-nimotuzumab for immunoPET imaging of epidermal growth factor receptor I

RATIONALE: Epidermal growth factor receptor (EGFR) upregulation is associated with enhanced proliferation and drug resistance in a number of cancers. Nimotuzumab is a humanized monoclonal antibody with high affinity for EGFR. The objective of this study was to determine if (89)Zr-DFO-nimotuzumab cou...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Chekol, Rufael, Solomon, Viswas Raja, Alizadeh, Elahe, Bernhard, Wendy, Fisher, Darrell, Hill, Wayne, Barreto, Kris, DeCoteau, John Francis, Parada, Angel Casaco, Geyer, Clarence Ronald, Fonge, Humphrey
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908310/
https://ncbi.nlm.nih.gov/pubmed/29682209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24965
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