Pre-clinical study of IRDye800CW-nimotuzumab formulation, stability, pharmacokinetics, and safety

BACKGROUND: Epidermal growth factor receptor (EGFR) is a target for cancer therapy as it is overexpressed in a wide variety of cancers. Therapeutic antibodies that bind EGFR are being evaluated in clinical trials as imaging agents for positron emission tomography and image-guided surgery. However, s...

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Vydáno v:BMC Cancer
Hlavní autoři: Bernhard, Wendy, Barreto, Kris, El-Sayed, Ayman, Gonzalez, Carolina, Viswas, Raja Solomon, Toledo, Darien, Casaco, Angel, DeCoteau, John, Fonge, Humphrey, Geyer, Clarence Ronald
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953729/
https://ncbi.nlm.nih.gov/pubmed/33711962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08003-3
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