Inhibition of Lysophosphatidic Acid Receptor-2 Expression by RNA Interference Decreases Lysophosphatidic Acid-induced Urokinase Plasminogen Activator Activation, Cell Invasion, and Migration in Ovarian Cancer SKOV-3 Cells

AIM: To explore the role of lysophosphatidic acid receptor-2 (LPA(2)) in regulating lysophosphatidic acid (LPA)-induced urokinase plasminogen activator (uPA) activation, cell invasion, and migration in human ovarian cancer cell line SKOV-3. METHODS: SKOV-3 cells were stimulated with LPA. Cell supern...

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Detalhes bibliográficos
Main Authors: Wang, Gui-li, Wen, Ze-qing, Xu, Wan-peng, Wang, Zhi-yu, Du, Xue-lian, Wang, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: Croatian Medical Schools 2008
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359884/
https://ncbi.nlm.nih.gov/pubmed/18461672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3325/cmj.2008.2.175
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