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Protein kinase Cα-CARMA3 signaling axis links Ras to NF-κB for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells

We reported previously that a signaling pathway consisting of G(i)-Ras-NF-κB mediates lysophosphatidic acid (LPA)-induced urokinase plasminogen activator (uPA) upregulation in ovarian cancer cells. However, it is not clear what signaling components link Ras to nuclear factor (NF)-κB for this LPA-ind...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Mahanivong, C, Chen, HM, Yee, SW, Pan, ZK, Dong, Z, Huang, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513671/
https://ncbi.nlm.nih.gov/pubmed/17724468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210746
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