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Requirement of Nanog dimerization for stem cell self-renewal and pluripotency

Pluripotency of embryonic stem (ES) cells is maintained by transcription factors that form a highly interconnected protein interaction network surrounding the homeobox protein Nanog. Enforced expression of Nanog in mouse ES (mES) cells promotes self-renewal and alleviates their requirement for leuke...

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Autors principals: Wang, Jianlong, Levasseur, Dana N., Orkin, Stuart H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359802/
https://ncbi.nlm.nih.gov/pubmed/18436640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802288105
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