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Requirement of Nanog dimerization for stem cell self-renewal and pluripotency
Pluripotency of embryonic stem (ES) cells is maintained by transcription factors that form a highly interconnected protein interaction network surrounding the homeobox protein Nanog. Enforced expression of Nanog in mouse ES (mES) cells promotes self-renewal and alleviates their requirement for leuke...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2359802/ https://ncbi.nlm.nih.gov/pubmed/18436640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802288105 |
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