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Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells

Embryonic stem (ES) cells offer insight into early developmental fate decisions, and their controlled differentiation may yield vast regenerative potential. The molecular determinants supporting ES cell self-renewal are incompletely understood. The homeodomain proteins Nanog and Oct4 are essential f...

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Detalhes bibliográficos
Main Authors: Levasseur, Dana N., Wang, Jianlong, Dorschner, Michael O., Stamatoyannopoulos, John A., Orkin, Stuart H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259027/
https://ncbi.nlm.nih.gov/pubmed/18283123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1606308
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