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Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia

BACKGROUND: At present pathogenic mechanisms of cancer cachexia are poorly understood. Previous evidence in animal models implicates the melanocortin-4 receptor gene (MC4R) in the development of cancer cachexia. In humans, MC4R mutations that lead to an impaired receptor function are associated with...

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Detalhes bibliográficos
Main Authors: Knoll, Susanne, Zimmer, Sabiene, Hinney, Anke, Scherag, André, Neubauer, Andreas, Hebebrand, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359760/
https://ncbi.nlm.nih.gov/pubmed/18377640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-85
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