Melanocortin-4 Receptor Gene Variant I103 Is Negatively Associated with Obesity

Several rare mutations in the melanocortin-4 receptor gene (MC4R) predispose to obesity. For the most common missense variant V103I (rs2229616), however, the previously reported similar carrier frequencies in obese and nonobese individuals are in line with in vitro studies, which have not shown a fu...

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Autors principals: Geller, Frank, Reichwald, Kathrin, Dempfle, Astrid, Illig, Thomas, Vollmert, Caren, Herpertz, Stephan, Siffert, Winfried, Platzer, Matthias, Hess, Claudia, Gudermann, Thomas, Biebermann, Heike, Wichmann, H.-Erich, Schäfer, Helmut, Hinney, Anke, Hebebrand, Johannes
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Human Genetics 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193776/
https://ncbi.nlm.nih.gov/pubmed/14973783
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