Genome Wide Association (GWA) Study for Early Onset Extreme Obesity Supports the Role of Fat Mass and Obesity Associated Gene (FTO) Variants

BACKGROUND: Obesity is a major health problem. Although heritability is substantial, genetic mechanisms predisposing to obesity are not very well understood. We have performed a genome wide association study (GWA) for early onset (extreme) obesity. METHODOLOGY/PRINCIPAL FINDINGS: a) GWA (Genome-Wide...

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Autors principals: Hinney, Anke, Nguyen, Thuy Trang, Scherag, André, Friedel, Susann, Brönner, Günter, Müller, Timo Dirk, Grallert, Harald, Illig, Thomas, Wichmann, H.-Erich, Rief, Winfried, Schäfer, Helmut, Hebebrand, Johannes
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137937/
https://ncbi.nlm.nih.gov/pubmed/18159244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001361
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