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Drug-induced senescence bystander proliferation in prostate cancer cells in vitro and in vivo

Senescence is a distinct cellular response induced by DNA-damaging agents and other sublethal stressors and may provide novel benefits in cancer therapy. However, in an ageing model, senescent fibroblasts were found to stimulate the proliferation of cocultured cells. To address whether senescence in...

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Bibliografiske detaljer
Main Authors: Ewald, J A, Desotelle, J A, Almassi, N, Jarrard, D F
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359629/
https://ncbi.nlm.nih.gov/pubmed/18349844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604288
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