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Inter- and intraspecies polymorphisms in the cholecystokinin-B/gastrin receptor alter drug efficacy

The brain cholecystokinin-B/gastrin receptor (CCK-BR) is a major target for drug development because of its postulated role in modulating anxiety, memory, and the perception of pain. Drug discovery efforts have resulted in the identification of small synthetic molecules that can selectively activate...

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Detalhes bibliográficos
Main Authors: Kopin, Alan S., McBride, Edward W., Gordon, Michelle C., Quinn, Suzanne M., Beinborn, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23582/
https://ncbi.nlm.nih.gov/pubmed/9380756
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