Inter- and intraspecies polymorphisms in the cholecystokinin-B/gastrin receptor alter drug efficacy

The brain cholecystokinin-B/gastrin receptor (CCK-BR) is a major target for drug development because of its postulated role in modulating anxiety, memory, and the perception of pain. Drug discovery efforts have resulted in the identification of small synthetic molecules that can selectively activate...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kopin, Alan S., McBride, Edward W., Gordon, Michelle C., Quinn, Suzanne M., Beinborn, Martin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23582/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380756/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.11043
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