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Inter- and intraspecies polymorphisms in the cholecystokinin-B/gastrin receptor alter drug efficacy

The brain cholecystokinin-B/gastrin receptor (CCK-BR) is a major target for drug development because of its postulated role in modulating anxiety, memory, and the perception of pain. Drug discovery efforts have resulted in the identification of small synthetic molecules that can selectively activate...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kopin, Alan S., McBride, Edward W., Gordon, Michelle C., Quinn, Suzanne M., Beinborn, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23582/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.11043
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