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The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid

The γ-aminobutyric acid type A (GABA(A)) receptor is a transmitter-gated ion channel mediating the majority of fast inhibitory synaptic transmission within the brain. The receptor is a pentameric assembly of subunits drawn from multiple classes (α(1–6), β(1–3), γ(1–3), δ(1), and ɛ(1)). Positive allo...

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Detalhes bibliográficos
Main Authors: Belelli, Delia, Lambert, Jeremy J., Peters, John A., Wafford, Keith, Whiting, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23576/
https://ncbi.nlm.nih.gov/pubmed/9380754
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