The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid
The γ-aminobutyric acid type A (GABA(A)) receptor is a transmitter-gated ion channel mediating the majority of fast inhibitory synaptic transmission within the brain. The receptor is a pentameric assembly of subunits drawn from multiple classes (α(1–6), β(1–3), γ(1–3), δ(1), and ɛ(1)). Positive allo...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.11031 |
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