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Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias

Panhandle PCR amplifies genomic DNA with known 5′ and unknown 3′ sequences from a template with an intrastrand loop schematically shaped like a pan with a handle. We used panhandle PCR to clone MLL genomic breakpoints in two pediatric treatment-related leukemias. The karyotype in a case of treatment...

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Tallennettuna:
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Megonigal, Maureen D., Rappaport, Eric F., Jones, Douglas H., Kim, Caroline S., Nowell, Peter C., Lange, Beverly J., Felix, Carolyn A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1997
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326653/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11583
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