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Application of an intramolecular dipolar cycloaddition to an asymmetric synthesis of the fully oxygenated tricyclic core of the stemofoline alkaloids

An intramolecular non-stabilized azomethine ylide dipolar cycloaddition was applied toward the first non-racemic synthesis of the fully-oxygenated bridged pyrrolizidine core (45) of (+)-stemofoline (1) in eleven steps from a commercially available starting material.

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Библиографические подробности
Главные авторы: Carra, Ryan J., Epperson, Matthew T., Gin, David Y.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2352155/
https://ncbi.nlm.nih.gov/pubmed/18443655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.02.008
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