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Recombination by the mouse immunoglobulin κ deleting element RS promotes immune tolerance and Igλ B cell production
The recombining sequence (RS) of mouse and its human equivalent, the kappa deleting element (kde), are sequences found at the 3′ end of the immunoglobulin κ locus that rearrange to inactivate the κ-locus in developing B cells. RS recombination correlates with Igλ expression and plays a role in recep...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2351955/ https://ncbi.nlm.nih.gov/pubmed/18261939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.12.011 |
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