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An immunoglobulin Cκ-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system

Understanding immune tolerance mechanisms is a major goal of immunology research, but mechanistic studies have generally required the use of mouse models carrying untargeted or targeted antigen receptor transgenes, which distort lymphocyte development and therefore preclude analysis of a truly norma...

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Bibliografiske detaljer
Main Authors: Ait-Azzouzene, Djemel, Verkoczy, Laurent, Peters, Jorieke, Gavin, Amanda, Skog, Patrick, Vela, José Luis, Nemazee, David
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212821/
https://ncbi.nlm.nih.gov/pubmed/15738053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041854
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