Role of tyrosine phosphorylation of a cellular protein in adeno-associated virus 2-mediated transgene expression

The adeno-associated virus 2 (AAV), a single-stranded DNA-containing, nonpathogenic human parvovirus, has gained attention as a potentially useful vector for human gene therapy. However, the single-stranded nature of the viral genome significantly impacts upon the transduction efficiency, because th...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Qing, Keyun, Wang, Xu-Shan, Kube, Dagmar M., Ponnazhagan, Selvarangan, Bajpai, Anil, Srivastava, Arun
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23516/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380728/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.10879
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