Role of tyrosine phosphorylation of a cellular protein in adeno-associated virus 2-mediated transgene expression

The adeno-associated virus 2 (AAV), a single-stranded DNA-containing, nonpathogenic human parvovirus, has gained attention as a potentially useful vector for human gene therapy. However, the single-stranded nature of the viral genome significantly impacts upon the transduction efficiency, because th...

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Bibliographic Details
Main Authors: Qing, Keyun, Wang, Xu-Shan, Kube, Dagmar M., Ponnazhagan, Selvarangan, Bajpai, Anil, Srivastava, Arun
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC23516/
https://ncbi.nlm.nih.gov/pubmed/9380728
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