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Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide

Although cellular proteins degraded by proteasomes are the source of most antigenic peptides presented on major histocompatibility complex class I molecules, it is unknown whether the eight- to nine-residue peptides that fit in the binding groove of class I molecules are directly produced by proteas...

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Bibliographic Details
Main Authors: Craiu, Abie, Akopian, Tatos, Goldberg, Alfred, Rock, Kenneth L.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC23505/
https://ncbi.nlm.nih.gov/pubmed/9380723
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