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Close Correspondence between the Essential Protein Motions from Principal Component Analysis of Multiple HIV-1 Protease Structures and Elastic Network Modes

The large number of available HIV-1 protease structures provides a remarkable sampling of conformations of the different conformational states, which can be viewed as direct structural information about its dynamics. After structure matching, we apply principal component analysis (PCA) to obtain the...

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Detaylı Bibliyografya
Asıl Yazarlar: Yang, Lei, Song, Guang, Carriquiry, Alicia, Jernigan, Robert L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2350220/
https://ncbi.nlm.nih.gov/pubmed/18275822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.12.011
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