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Close Correspondence between the Essential Protein Motions from Principal Component Analysis of Multiple HIV-1 Protease Structures and Elastic Network Modes
The large number of available HIV-1 protease structures provides a remarkable sampling of conformations of the different conformational states, which can be viewed as direct structural information about its dynamics. After structure matching, we apply principal component analysis (PCA) to obtain the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2350220/ https://ncbi.nlm.nih.gov/pubmed/18275822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.12.011 |
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