Activated Glucocorticoid Receptor Interacts with the INHAT Component Set/TAF-Iβ and Releases it from a Glucocorticoid-responsive Gene Promoter, Relieving Repression: Implications for the Pathogenesis of Glucocorticoid Resistance in Acute Undifferentiated Leukemia with Set-Can Translocation

Set/template-activating factor (TAF)-Iβ, part of the Set-Can oncogene product found in acute undifferentiated leukemia, is a component of the inhibitor of acetyltransferases (INHAT) complex. Set/TAF-Iβ interacted with the DNA-binding domain of the glucocorticoid receptor (GR) in yeast two-hybrid scr...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Ichijo, Takamasa, Chrousos, George P., Kino, Tomoshige
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2350211/
https://ncbi.nlm.nih.gov/pubmed/18096310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2007.10.014
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